Projects: Program I. Biomedical and Dental Non-Invasive Diagnostic Imaging Techniques and Biosensor Technologies

Program I: Biomedical Photoacoustic and Thermophotonic Technology & Instrumentation Development

1. Non-invasive laser-based technology for continuous or intermittent measurement of blood glucose (and blood alcohol content)

   The non-invasive measurement of blood glucose has long been a “holy grail” in biosensor science and technology [1]. For more…
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2. Development of a high-resolution photothermal coherence tomography clinical imager for detection and 3-D mapping of early dental caries

   Dental caries remains the most prevalent chronic disease in both children and adults, imposing significant financial and societal burdens on…
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3. Development of Multi-Spectral Frequency-Domain Photoacoustic imaging

   Our PAR imager operating with linear frequency modulation (LFM chirp) of a CW laser beam [37] exhibits superior signal-to-noise ratio…
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4. Pre-clinical Small-Animal Functional Photothermal Coherence Imaging

   Pre-clinical imaging technologies are excellent tools for assessment of anatomical, physiological and functional parameters at molecular and cellular levels in…
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5. Development of noninvasive bone density biosensors

   Osteoporosis (OP) is a major public health problem in Canada and around the world. Fractures from osteoporosis are more common…
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6. Development of Photoacoustic Radar (PAR) imaging

   Photoacoustic (PA) imaging modalities are internationally regarded as a very promising complement or alternative to conventional magnetic resonance imaging (MRI),…
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7. Truncated-Correlation Photothermal Coherence Tomography (TC-PCT)

   This is a revolutionary IR-camera-based dynamic imaging technique recently pioneered in the CADIPT [1,2]. The high axial resolution due to…
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