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Home List Publications: Biosensors, Biothermophotonics and Biomedical Photoacoustics of Hard and Soft Tissues
Biosensors, Biothermophotonics and Biomedical Photoacoustics of Hard and Soft Tissues
Detection and Monitoring of Early Dental Caries and Erosion Using Three-Dimensional enhanced Truncated Correlation Photothermal Coherence Tomography (eTC-PCT) Imaging
S. Roointan, P. Tavakolian, K. S. Sivagurunathan, A. Mandelis, and S. H. Abrams, « Detection and Monitoring of Early Dental Caries and Erosion Using Three-Dimensional enhanced Truncated Correlation Photothermal Coherence Tomography (eTC-PCT) Imaging », J. Biomed. Opt. 26 (4), 046004 (23 pages), April 2021 - PDF
Non-Invasive In-Vivo 3-D Imaging of Small Animals Using Spatially Filtered Enhanced Truncated-Correlation Photothermal Coherence Tomography
P. Tavakolian, S. Roointan, A. Mandelis and W. Shi, « Non-Invasive In-Vivo 3-D Imaging of Small Animals Using Spatially Filtered Enhanced Truncated-Correlation Photothermal Coherence Tomography », (Nature) Scientific Reports 10, 13743 (10 pages) (2020). https://doi.org/10.1038/s41598-020-70815-3 - PDF
3D Dental Subsurface Imaging Using Enhanced Truncated-Correlation Photothermal Coherence Tomography
S. Roointan, P. Tavakolian, K. S. Sivagurunathan, M. Floryan, A. Mandelis, and S. H. Abrams, “3D Dental Subsurface Imaging Using Enhanced Truncated-Correlation Photothermal Coherence Tomography”, (Nature) Scientific Reports 9, 16788 (12 pages) (2019). https://doi.org/10.1038/s41598-019-53170-w - PDF
« Interference-free Detection of Lipid-laden Atherosclerotic Plaques by 3D Co-registration of Frequency-Domain Differential Photoacoustic and Ultrasound Radar Imaging
S.S.S Choi, B. Lashkari, A. Mandelis, J. J. Weyers, A. Boyes, S. F. Foster, N. Alves, and B. Courtney, « Interference-free Detection of Lipid-laden Atherosclerotic Plaques by 3D Co-registration of Frequency-Domain Differential Photoacoustic and Ultrasound Radar Imaging» (Nature) Scientific Reports 9, 12400 (11 pages) (2019) https://doi.org/10.1038/s41598-019-48896-6 - PDF
Review of the state of the art in cardiovascular endoscopy imaging of atherosclerosis using photoacoustic techniques with pulsed and continuous-wave optical excitations
Sung Soo Sean Choi, Andreas Mandelis, "Review of the state of the art in cardiovascular endoscopy imaging of atherosclerosis using photoacoustic techniques with pulsed and continuous-wave optical excitations," J. Biomed. Opt. 24(8), 080902 (pages 1-15) (2019), doi: 10.1117/1.JBO.24.8.080902. - PDF
« Waveform Engineering Analysis of Photoacoustic Radar Chirp Parameters for Spatial Resolution and SNR Optimization
N. Baddour, Z. Sun and A. Mandelis, « Waveform Engineering Analysis of Photoacoustic Radar Chirp Parameters for Spatial Resolution and SNR Optimization », Photoacoustics 14, 49-66 (2019) https://doi.org/10.1016/j.pacs.2019.04.003 - PDF
Noninvasive in-vivo glucose detection in human finger interstitial fluid using wavelength-modulated differential photothermal radiometry
X. Guo, D. Zhang, K. Shojaei-Asanjan, K. Sivagurunathan, A. Melnikov, P. Song, and A. Mandelis « Noninvasive in-vivo glucose detection in human finger interstitial fluid using wavelength-modulated differential photothermal radiometry », J. Biophotonics 12 : e201800441, 1 – 8 (July 2019) / doi.org: 10.1002/jbio.201800441. - PDF
« Truncated-correlation photothermal coherence tomography derivative imaging modality for small animal in vivo early tumor detection
H. Zhang, P. Tavakolian, K. Sivagurunathan, A. Mandelis, W. Shi and F-F. Liu, « Truncated-correlation photothermal coherence tomography derivative imaging modality for small animal in vivo early tumor detection », Optics Letters 44 (3) 675 – 678 (1 Feb. 2019) https://doi.org/10.1364/OL.44.000675. - PDF
Frequency-Domain Differential Photoacoustic Radar: Theory and Validation for Ultra-Sensitive Atherosclerotic Plaque Imaging
S. S. S. Choi, B. Lashkari,A. Mandelis, J. Son,N. Alves-Kotzev, S. F. Foster,M. Harduar and B. Courtney, «Frequency-Domain Differential Photoacoustic Radar: Theory and Validation for Ultra-Sensitive Atherosclerotic Plaque Imaging », J. Biomed. Opt. 24(6), 066003 (12 pages) (2019), doi: 10.1117/1.JBO.24.6.066003. Research and paper highlighted by the SPIE at a press release on its website:
https://www.photonics.com/Articles/New_Imaging_Technique_Targets_Cholesterol_in/p6/v177/i1169/a64823 - PDF
Highly sensitive and specific noninvasive in-vivo alcohol detection using wavelength-modulated differential photothermal radiometry
X. Guo, K. Shojaei-Asanjan, D. Zhang, K. Sivagurunathan, Q. Sun, P. Song, A. Mandelis, B. Chen, M. Goledzinowski, Q. Zhou, and F. Comeau, « Highly sensitive and specific noninvasive in-vivo alcohol detection using wavelength-modulated differential photothermal radiometry », Biomed. Opt. Express 9 (10), 4638 – 4648 (1 Oct. 2018) https://doi.org/10.1364/BOE.9.004638 - PDF
The Application of Frequency-Domain Photoacoustics to TemperatureDependent Measurements of the Grüneisen Parameter in lipids
S. Liang, B. Lashkari, S.s. S. Choi, V. Ntziachristos and A. Mandelis, « The Application of Frequency-Domain Photoacoustics to TemperatureDependent Measurements of the Grüneisen Parameter in lipids », Photoacoustics 11, 56 – 64 (Sept. 2018). - PDF
Detection of caries around Glass Ionomer and Compomer restorations using four different modalities in vitro
T. Abrams, S. Abrams, K. Sivagurunathan, V. Morvan, W. Hellen, G. Elman, B. Amaechi and A. Mandelis, « Detection of caries around Glass Ionomer and Compomer restorations using four different modalities in vitro », Dentistry Journal 6 (47), 1 - 13 (2018) / DOI 10.3390/dj6030047 - PDF
Correlation with caries lesion depth of The Canary System, DIAGNOdent and ICDAS II
S. H. Abrams, K. Sivagurunathan, J. D. Silvertown, B. Wong, A. Hellen, A. Mandelis, W. M. P. Hellen, G. I. Elman, S.M. Mathew, P.K. Mensinkai, and B. T. Amaechi "Correlation with caries lesion depth of The Canary System, DIAGNOdent and ICDAS II", Open Dentistry J. 11, 679 – 689 (2017) / DOI 10.2174/1874210601711010679 - PDF
Multi-centre clinical evaluation of photothermal radiometry and luminescence correlated with international benchmarks for caries detection
J. D. Silvertown, K. S. Sivagurunathan, J. Kennedy, J-S Jeon, A. Mandelis, A. Hellen, W. Hellen, G. Elman, R. Ehrlich, R.y Chouljian, Y. Finer, S. H. Abrams, and B. T. Amaechi, « Multi-centre clinical evaluation of photothermal radiometry and luminescence correlated with international benchmarks for caries detection », Open Dentistry J. 11, 636 – 647 (2017) / DOI 10.2174/1874210601711010636 - PDF
Photoacoustic resonance by spatial filtering of focused ultrasound transducers
D. Kang, B. Lashkari, and A. Mandelis, « Photoacoustic resonance by spatial filtering of focused ultrasound transducers », Optics Lett. 42 (4), 655 – 658 (2017) /DOI 10.1364/OL.42.000655 - PDF
Imaging Cancer with Photoacoustic Radar
A. Mandelis, «Imaging Cancer with Photoacoustic Radar», Physics Today 70 (5), May 2017, pp. 42-48 - PDF
Wavelength-Modulated Differential Photoacoustic Radar Imager (WM-DPARI): Accurate Monitoring of Absolute Hemoglobin Oxygen Saturation
S. S. (Sean) Choi, B. Lashkari, E. Dovlo and A. Mandelis, «Wavelength-Modulated Differential Photoacoustic Radar Imager (WM-DPARI): Accurate Monitoring of Absolute Hemoglobin Oxygen Saturation», Biomedical Opt. Express 7 (7), 2586 – 2596 (1 July 2016) DOI:10.1364/BOE.7.002586. - PDF
Wavelength-Modulated Differential Photoacoustic Spectroscopy (WM-DPAS) for noninvasive early cancer detection and tissue hypoxia monitoring
Sung soo (Sean) Choi, Andreas Mandelis, Xinxin Guo, Bahman Lashkari, Stephan Kellnberger, and Vasilis Ntziachristos, "Wavelength-Modulated Differential Photoacoustic Spectroscopy (WM-DPAS) for noninvasive early cancer detection and tissue hypoxia monitoring", J. Biophotonics, 9, No. 4, 388–395 (2016) / DOI 10.1002/jbio.201500131. (WM-DPAS cover picture selected for Vol. 9, issue 4 of the journal: http://onlinelibrary.wiley.com/doi/10.1002/jbio.v9.4/issuetoc) - PDF
Microwave-heating-coupled photoacoustic radar signals for tissue diagnostic imaging
W. Wang and A. Mandelis, «Microwave-heating-coupled photoacoustic radar signals for tissue diagnostic imaging », J. Biomed. Opt. 21(6), 066018 (8 pages) (June 2016) / http://dx.doi.org/10.1117/1.JBO.21.6.066018 - PDF
« Frequency-domain Photoacoustic Phase Spectroscopy: A Fluence-independent Approach for Quantitative Probing of Hemoglobin Oxygen Saturation
B. Lashkari, S. S. (Sean) Choi, E. Dovlo, S. Dhody and A. Mandelis, « Frequency-domain Photoacoustic Phase Spectroscopy: A Fluence-independent Approach for Quantitative Probing of Hemoglobin Oxygen Saturation », IEEE J. Selected Topics Quantum Electronics (JSTQE), Special Issue on Biophotonics 22 (3), 6801010 (10 pages) (May/June 2016). DOI: 10.1109/JSTQE.2015.2494532 - PDF
SNR and Contrast Enhancement Techniques for the Photoacoustic Radar Imaging
W. Wang and A. Mandelis, «SNR and Contrast Enhancement Techniques for the Photoacoustic Radar Imaging », Int. J. Thermophys. 37 (74) 8 pages, (July 2016). DOI: 10.1007/s10765-016-2079-4 - PDF
Co-registered Frequency-Domain Photoacoustic Radar and Ultrasound System for Subsurface Imaging in Turbid Media
E. Dovlo, B. Lashkari and A. Mandelis, «Co-registered Frequency-Domain Photoacoustic Radar and Ultrasound System for Subsurface Imaging in Turbid Media», Int. J. Thermophys. 37 (29) 8 pages, (2016). DOI: 10.1007/s10765-016-2041-5 - PDF
Quantitative Phase-filtered Wavelength-Modulated Differential Photoacoustic Radar tumor hypoxia imaging toward early cancer detection
E. Dovlo, B. Lashkari, S. s. S. Choi, A. Mandelis, W. Shi, and F-F. Liu, « Quantitative Phase-filtered Wavelength-Modulated Differential Photoacoustic Radar tumor hypoxia imaging toward early cancer detection », J. Biophotonics 10 (9), 1134 - 1142 (Sept. 2017)/ DOI 10.1002/jbio.201600168 - PDF
Photoacoustic Radar Phase-Filtered Spatial Resolution and Co-registered Ultrasound Image Enhancement for Tumor Detection
E. Dovlo, B. Lashkari, A. Mandelis, W. Shi, F-F Liu, « Photoacoustic Radar Phase-Filtered Spatial Resolution and Co-registered Ultrasound Image Enhancement for Tumor Detection », Biomed. Optics Express 6 (3), 1003 - 1009 (1 Mar 2015). - PDF
Bone Composition Diagnostics: Photoacoustics Versus Ultrasound
L. Yang, B. Lashkari, A. Mandelis, and J. W.Y.Tan, "Bone Composition Diagnostics: Photoacoustics Versus Ultrasound", Int. J. Thermophys. 36 (5-6), 862-867 (May-June 2015) DOI: 10.1007/s10765-014-1701-6 - PDF
Combined Photoacoustic Ultrasound and Beam Deflection Signal Monitoring of Gold Nanoparticle Agglomerate Concentrations in Tissue Phantoms Using a Pulsed Nd:YAG Laser
M. E. Khosroshahi and A. Mandelis, "Combined Photoacoustic Ultrasound and Beam Deflection Signal Monitoring of Gold Nanoparticle Agglomerate Concentrations in Tissue Phantoms Using a Pulsed Nd:YAG Laser", Int. J. Thermophys. 36 (5-6), 880-890 (May-June 2015) DOI: 10.1007/s10765-014-1773-3 - PDF
Frequency-domain photo-thermo-acoustic and ultrasonic imaging of blood and opto-thermal effects of plasmonic nanoparticle concentrations
M. E. Khosroshahi, A. Mandelis and B. Lashkari "Frequency-domain photo-thermo-acoustic and ultrasonic imaging of blood and opto-thermal effects of plasmonic nanoparticle concentrations", J. Biomed. Opt. 20 (7), 076009 (12 pages) (July 2015). - PDF
Photoacoustic and ultrasound imaging of cancellous bone tissue
L. Yang, B. Lashkari, J. Tan and A. Mandelis, "Photoacoustic and ultrasound imaging of cancellous bone tissue", J. Biomed. Opt. 20(7), 076016 (12 pages) (2015). doi:10.1117/1.JBO.20.7.076016. - PDF
Simultaneous Dual-wavelength Photoacoustic Radar Image Generation Using Waveform Engineering with Mismatched Frequency Modulated Excitation
B. Lashkari, S. S. Choi, M. E. Khosroshahi, E. Dovlo and A. Mandelis, "Simultaneous Dual-wavelength Photoacoustic Radar Image Generation Using Waveform Engineering with Mismatched Frequency Modulated Excitation", Opt. Lett. 40 (7), 1145 – 1148 (April 1, 2015). - PDF
The Effect of Laser Power on Photothermoacoustic Imaging of Blood Containing Gold Nanoparticles and De-oxygenation using a Frequency-Domain Phased Array Probe: An In-vitro Assay
M. E. Khosroshahi, A. Mandelis and B. Lashkari, "The Effect of Laser Power on Photothermoacoustic Imaging of Blood Containing Gold Nanoparticles and De-oxygenation using a Frequency-Domain Phased Array Probe: An In-vitro Assay", Nanoscience & Technology: Open Access 2(1): 1-10 (2015). - PDF
Thermally Enhanced Photoacoustic Radar Imaging of Biotissues
Wei Wang and Andreas Mandelis, "Thermally Enhanced Photoacoustic Radar Imaging of Biotissues", Int. J. Thermophys. 36 (5-6), 900-904 (May-June 2015) DOI: 10.1007/s10765-015-1838-y - PDF
Wavelength-modulated Differential Photoacoustic Spectroscopy (WM-DPAS): Theory of a High-sensitivity Methodology For the Detection of Early-stage Tumors In Tissues
S. Choi, A. Mandelis, X. Guo, B. Lashkari, S. Kellnberger and V. Ntziachristos, "Wavelength-modulated Differential Photoacoustic Spectroscopy (WM-DPAS): Theory of a High-sensitivity Methodology For the Detection of Early-stage Tumors In Tissues", Int. J. Thermophys. 36 (5-6), 1305-1311 (May-June 2015) DOI: 10.1007/s10765-014-1710-5. - PDF
The Effect of Acoustic Impedance on Subsurface Absorber Geometry Reconstruction using 1D Frequency-Domain Photoacoustics
N. Baddour and A. Mandelis, « The Effect of Acoustic Impedance on Subsurface Absorber Geometry Reconstruction using 1D Frequency-Domain Photoacoustics », Photoacoustics 3 132–142 (2015). - PDF
Absolute calibration method of ethyl alcohol biosensor based on wavelength-modulated differential photothermal radiometry
Y. J. Liu , A. Mandelis and X. Guo, « Absolute calibration method of ethyl alcohol biosensor based on wavelength-modulated differential photothermal radiometry », Rev. Sci. Instrum. 86 (11), 115003 (6 pages) November 2015. http://dx.doi.org/10.1063/1.4935308 - PDF
Noninvasive in-vehicle alcohol detection with Wavelength-Modulated Differential Photothermal Radiometry
X. Guo, A. Mandelis, Y-J. Liu, B. Chen, Q. Zhou, and F. Comeau, "Noninvasive in-vehicle alcohol detection with Wavelength-Modulated Differential Photothermal Radiometry", Biomed. Optics Express 5 (7)2333-2340 (June 18, 2014)DOI:10.1364/BOE.5.002333. Paper selected for inclusion in Spotlight in Optics (OSA), www.opticsinfobase.org/spotlight July 25 (2014). - PDF
Truncated-correlation photothermal coherence tomography (TC-PCT) of artificially demineralized animal bones: 2- and 3-dimensional markers for mineral-loss monitoring
S.Kaiplavil, A.Mandelis and B. A. Amaechi, "Truncated-correlation photothermal coherence tomography (TC-PCT) of artificially demineralized animal bones: 2- and 3-dimensional markers for mineral-loss monitoring", J. Biomed. Opt. 19 (2), 026015 (14 pages) (February 2014). - PDF
Thermally Enhanced Depth Resolution of Photoacoustic Radar Imaging
W. Wang and A. Mandelis, "Thermally Enhanced Depth Resolution of Photoacoustic Radar Imaging", Biomed. Optics Express 5 (8) 2785 – 2790 (July 25, 2014) DOI:10.1364/BOE.5.002785. - PDF
The Application of Backscattered Ultrasound and Photoacoustic Signals for Assessment of Bone Collagen and Mineral Contents
B. Lashkari, L. Yang, and A. Mandelis, "The Application of Backscattered Ultrasound and Photoacoustic Signals for Assessment of Bone Collagen and Mineral Contents", Quant. Imaging Med. Surg., Special issue "Emerging Technologies in Biomedical Imaging" 5(1), 46 – 56 (2015). doi: 10.3978/j.issn.2223-4292.2014.11.11 - PDF
Photothermal tomography for the functional and structural evaluation and early mineral loss monitoring in bones
S. Kaiplavil, A. Mandelis,X. D. Wang, and T. Feng, "Photothermal tomography for the functional and structural evaluation and early mineral loss monitoring in bones", Biomedical Optics Express 5 (8), 2488-2502 (2014) [DOI:10.1364/BOE.5.002488]. - PDF
Co-registered photoacoustic and ultrasonic signatures of early bone density variations
B. Lashkari and A. Mandelis, "Co-registered photoacoustic and ultrasonic signatures of early bone density variations", J. Biomed. Opt. 19 (3), 036015 (11 pages) (2014) - PDF
Photoacoustic correlation signal-to-noise-ratio enhancement by coherent averaging and optical waveform optimization
S. Telenkov, R. Alwi, and A. Mandelis, "Photoacoustic correlation signal-to-noise-ratio enhancement by coherent averaging and optical waveform optimization", Rev. Sci. Instrum. 84, 104907 (1-7) (2013) [DOI: 10.1063/1.4825034]. - PDF
Features of the Frequency- and Time-Domain Photoacoustic Modalities
B. Lashkari and A. Mandelis, "Features of the Frequency- and Time-Domain Photoacoustic Modalities", Int. J. Thermophys. 34 (8-9), 1398-1404 (September 2013) [DOI 10.1007/s10765-013-1462-7]. - PDF
Applications of ultrasensitive wavelength-modulated differential photothermal radiometry to noninvasive glucose detection in blood serum
X. Guo, A. Mandelis, and B. Zinman, "Applications of ultrasensitive wavelength-modulated differential photothermal radiometry to noninvasive glucose detection in blood serum", J. Biophotonics 6, No. 11–12, 911–919 (2013) [/ DOI 10.1002/jbio.201200103] - PDF
Ultra-Deep Bone Diagnostics with Fat–Skin Overlayers Using New Pulsed Photothermal Radar
S. Kaiplavil and A. Mandelis, “Ultra-Deep Bone Diagnostics with Fat–Skin Overlayers Using New Pulsed Photothermal Radar”, Int. J. Thermophys. 34, (8-9), 1481-1488, September 2013 [DOI 10.1007/s10765-013-1399-x]. - PDF
In-Vitro Detection of Artificial Caries on Vertical Dental Cavity Walls Using Infrared Photothermal Radiometry and Modulated Luminescence
J. Kim, A. Mandelis, S. H. Abrams, J. T Vu and B. T. Amaechi, "In-Vitro Detection of Artificial Caries on Vertical Dental Cavity Walls Using Infrared Photothermal Radiometry and Modulated Luminescence", J. Biomed. Opt. 17 (12), 127001 (10 pages) (2012). DOI:10.1117/1.JBO.17.12.127001 - PDF
Detection of Dental Secondary Caries Using Frequency-Domain Infrared Photothermal Radiometry (PTR) and Modulated Luminescence (LUM)
J. Kim, A. Mandelis, A. Matvienko, S. Abrams, and B. T. Amaechi, "Detection of Dental Secondary Caries Using Frequency-Domain Infrared Photothermal Radiometry (PTR) and Modulated Luminescence (LUM)", Int. J. Thermophys. 33 (10-11), 1778-1786 (Nov. 2012) DOI 10.1007/s10765-012-1322-x. - PDF
Frequency-domain photoacoustic phased array probefor biomedical imaging applications
S. Telenkov, R. Alwi, A. Mandelis and A. Worthington, "Frequency-domain photoacoustic phased array probefor biomedical imaging applications", Opt. Lett. 36 ( 23) 4560-2 (Dec. 1, 2011) DOI: 10.1364/OL.36.004560. Paper selected for inclusion in Virtual Journal for Biomedical Optics (VJBO) http://www.opticsinfobase.org/vjbo/virtual_issue.cfm 2 (2), Feb.1, 2012. Section: Photoacoustic Imaging. - PDF
Non-invasive glucose detection in human skin using wavelength modulated differential laser photothermal radiometry
X. Guo, A. Mandelis, and B. Zinman, "Non-invasive glucose detection in human skin using wavelength modulated differential laser photothermal radiometry", Biomed. Opt. Express 3 (11) 3012–3021 (November 2012). - PDF
Non-invasive Glucose Measurements using Wavelength Modulated Differential Photothermal Radiometry (WM-DPTR)
X. Guo, A. Mandelis, and B. Zinman, "Non-invasive Glucose Measurements using Wavelength Modulated Differential Photothermal Radiometry (WM-DPTR)", Int. J. Thermophys. 33 (10-11),1814–1821 (2012). DOI 10.1007/s10765-012-1276-z. - PDF
On the sensitivity of thermophotonic lock-in imaging and polarized Raman spectroscopy to early dental caries diagnosis
N. Tabatabaei, A. Mandelis, M. Dehghany, K. H. Michaelian and B. T. Amaechi, "On the sensitivity of thermophotonic lock-in imaging and polarized Raman spectroscopy to early dental caries diagnosis", J. Biomed. Opt. 17 (2), 025002 (4 pages) (February 2012). - PDF
Silica-coated super paramagnetic iron oxide nanoparticles (SPION) as biocompatible contrast agents in biomedical photoacoustics
R. Alwi, S. Telenkov, A. Mandelis, T. Leshuk, F. Gu and Kirk Michaelian, "Silica-coated super paramagnetic iron oxide nanoparticles (SPION) as biocompatible contrast agents in biomedical photoacoustics", Biomed. Opt. Express 3 (10) 2500-2509 (Oct. 1, 2012). - PDF
Slow and fast ultrasonic wave detection improvement in human trabecular bones using Golay code modulation
B. Lashkari, A. Manbachi, A. Mandelis and R. S. C. Cobbold, "Slow and fast ultrasonic wave detection improvement in human trabecular bones using Golay code modulation", J. Acoust. Soc. Am. Express Letters 132 (3) EL222-228 (September 2012) [http://dx.doi.org/10.1121/1.4742729] - PDF
Study of Tissue Phantoms, Tissues, Contrast Agent with the Biophotoacoustic Radar and Comparison to Ultrasound Imaging for Deep Subsurface Imaging
R. Alwi, S. Telenkov, A. Mandelis, and F. Gu, "Study of Tissue Phantoms, Tissues, Contrast Agent with the Biophotoacoustic Radar and Comparison to Ultrasound Imaging for Deep Subsurface Imaging", Int. J. Thermophys. 33 (10-11), 1808-1813 (Nov. 2012). DOI 10.1007/s10765-012-1286-x. - PDF
Special Section Guest Editorial: Hard Tissue Optics and Related Methods
D. Fried, A. Mandelis and M. Morris, "Special Section Guest Editorial: Hard Tissue Optics and Related Methods", J. Biomed. Opt. 16 (7), 071401 (July 2011). doi:10.1117/1.3612191. - PDF
Quantitiative evaluation of the remineralization of artificially demineralized human enamel using photothermal radiometry and modulated luminescence
A. Hellen, A. Mandelis, Y. Finer and B. T. Amaechi, ”Quantitiative evaluation of the remineralization of artificially demineralized human enamel using photothermal radiometry and modulated luminescence”, J. Biophotonics 4, No. 11–12, 788–804 (2011) / DOI 10.1002/jbio.201100026. - PDF
Wavelength modulated differential photothermal radiometry: theory and experimental applications to glucose detection in water
A. Mandelis and X. Guo, “Wavelength modulated differential photothermal radiometry: theory and experimental applications to glucose detection in water”, Phys. Rev. E 84, 041917 (1 – 14) (2011). DOI: 10.1103/PhysRevE.84.041917 - PDF
Linear frequency modulation photoacoustic radar: Optimal bandwidth and signal-to-noise ratio for frequency-domain imaging of turbid media
B. Lashkari and A. Mandelis, "Linear frequency modulation photoacoustic radar: Optimal bandwidth and signal-to-noise ratio for frequency-domain imaging of turbid media", J. Acoust. Soc. Am. 130 (3) 1313 – 1324 (Sept. 2011). - PDF
Comparison between pulsed laser and frequency-domain photoacoustic modalities: Signal-to-noise ratio, contrast, resolution and maximum depth detectivity
B. Lashkari and A.Mandelis, "Comparison between pulsed laser and frequency-domain photoacoustic modalities: Signal-to-noise ratio, contrast, resolution and maximum depth detectivity", Rev. Sci. Instrum. 82, 094903 (1 – 14) (2011). - PDF
Quantitative evaluation of the kinetics of human enamel simulated caries using photothermal radiometry and modulated luminescence
A. Hellen, A. Mandelis, Y. Finer and B. T. Amaechi, “Quantitative evaluation of the kinetics of human enamel simulated caries using photothermal radiometry and modulated luminescence”, J. Biomed. Opt. 16 (7), 071406 (1- 13), (July 2011). doi:10.1117/1.3564909. Paper selected for inclusion in Virtual Journal of Biological Physics Research (VJBIO) http://www.vjbio.org, 22 (2), July 15, 2011. Section: Instrumentation Development. - PDF
Thermophotonic lock-in imaging of early demineralized and carious lesions in human teeth
N. Tabatabaei, A. Mandelis and B. T. Amaechi, ”Thermophotonic lock-in imaging of early demineralized and carious lesions in human teeth”, J. Biomed. Opt. 16 (7), 071402 (1 – 10) (July 2011). doi:10.1117/1.3564890. Paper selected for inclusion in Virtual Journal of Biological Physics Research (VJBIO) http://www.vjbio.org, 22 (2), July 15, 2011. Section: Instrumentation Development. - PDF
Optothermophysical properties ofdemineralized human dental enamel determined using photothermally generated diffuse photon density and thermal wave fields
A. Hellen, A. Matvienko, A. Mandelis, Y. Finer and B. T. Amaechi, "Optothermophysical properties ofdemineralized human dental enamel determined using photothermally generated diffuse photon density and thermal wave fields", Appl. Opt. 49 (36), 6938 – 6951 (20 Dec. 2010). - PDF
Signal-to-noise analysis of biomedical photoacoustic measurements in time- and frequency-domains
S. Telenkov and A. Mandelis, "Signal-to-noise analysis of biomedical photoacoustic measurements in time- and frequency-domains", Rev. Sci. Instrum. 81, 124901 (1 -7) (2010). - PDF
Robust multi-parameter evaluation method of optical and thermal properties of a layered tissue structure using photothermal radiometry
A. Matvienko, A. Mandelis and S. Abrams, " Robust multi-parameter evaluation method of optical and thermal properties of a layered tissue structure using photothermal radiometry", Appl. Opt. 48 (17), 3192 – 3203 (June 2009). - PDF
Dynamic photophysical processes in laser irradiated human cortical skull bone measured by means of modulated luminescence
A. Mandelis, C.-H. Kwan and A. Matvienko, "Dynamic photophysical processes in laser irradiated human cortical skull bone measured by means of modulated luminescence", Phys. Rev. E 80, 021920 (14 pages) (August 2009). - PDF
Frequency-domain photothermoacoustics: alternative imaging modality of biological tissues
S. Telenkov, A. Mandelis, B. Lashkari and M. Forcht, "Frequency-domain photothermoacoustics: alternative imaging modality of biological tissues", Special Issue on Applied Biophysics; J. Appl. Phys. 105, 102029 (8 pages) (May 15, 2009). - PDF
Photoacoustic Radar imaging signal-to-noise ratio, contrast and resolution enhancement using nonlinear chirp modulation
B. Lashkari and A. Mandelis, "Photoacoustic Radar imaging signal-to-noise ratio, contrast and resolution enhancement using nonlinear chirp modulation", Opt. Lett. 35, 1623 - 1625 (2010). - PDF
Photothermoacoustic imaging of biological tissues: maximum depth characterization comparison of time- and frequency-domain measurements
S. Telenkov and A. Mandelis, "Photothermoacoustic imaging of biological tissues: maximum depth characterization comparison of time- and frequency-domain measurements", J. Biomed. Opt. 14 (4), 4-044025 (12 pages) (July/August 2009). - PDF
Preface to Special Topic: Applid Biophysics
A. Mandelis, G. J. Diebold, T. Kitamori, A. Hibara and I. A. Vitkin, "Preface to Special Topic: Applid Biophysics" , J. Appl. Phys. 105, 101901 (2 pages), May 15, 2009). - PDF
Theoretical analysis of coupled diffuse-photon-density and thermal-wave field depth profiles photothermally generated in layered turbid dental structures.
A. Matvienko, A. Mandelis, R.J. Jeon, and S. H. Abrams, "Theoretical analysis of coupled diffuse-photon-density and thermal-wave field depth profiles photothermally generated in layered turbid dental structures." Special Issue on Applied Biophysics; J. Appl. Phys. 105, 102022 (15 pages) (May 15, 2009). - PDF
In Vitro Detection of Enamel and Root caries Using Photothermal Radiometry and Modulated Luminescence
R. J. Jeon, A. Hellen, A. Matvienko, A. Mandelis, S. H. Abrams and B. T. Amaechi, "In Vitro Detection of Enamel and Root caries Using Photothermal Radiometry and Modulated Luminescence", J. Biomed. Opt. 13 (3) 034025 (11 pages) (May/June 2008). - PDF
Frequency-domain photothermoacoustic signal amplitude dependence on the optical properties of water: turbid polyvinyl chloride-plastisol system
G. M. Spirou, A. Mandelis, I. A. Vitkin and W. M. Whelan, "Frequency-domain photothermoacoustic signal amplitude dependence on the optical properties of water: turbid polyvinyl chloride-plastisol system", Appl. Opt. 47 (No. 4) 2564 – 2573 (10 May 2008). Paper selected for inclusion in Virtual Journal of Biomedical Optics (http://vjbo.osa.org/virtual_issue.cfm), 3 (6), June 17, 2008. - PDF
Detection of Interproximal Demineralized Lesions on Human Teeth in vitro Using Frequency-Domain Infrared Photothermal Radiometry and Modulated Luminescence
R. J. Jeon, A. Matvienko, A. Mandelis, S. H. Abrams, B. T. Amaechi and G. Kulkarni, "Detection of Interproximal Demineralized Lesions on Human Teeth in vitro Using Frequency-Domain Infrared Photothermal Radiometry and Modulated Luminescence", J. Biomed. Opt. 12 (3), 034028 (1-13) (May/June 2007). Selected for the Virtual Journal of Biological Physics Research: (http://www.vjbio.org/) , 12, 034028 (1-13) (July 2007). - PDF
Fourier-Domain Biophotoacoustic Sub-surface Depth Selective Amplitude and Phase Imaging of Turbid Phantoms and Biological Tissue
S. A. Telenkov and A. Mandelis, "Fourier-Domain Biophotoacoustic Sub-surface Depth Selective Amplitude and Phase Imaging of Turbid Phantoms and Biological Tissue", J. Biomed. Opt. 11 (4), 044006 (10 pages) (July/Aug. 2006). - PDF
Laser-Induced Photo-thermo-acoustic Pressure-Wave Pulses in a Polystyrene Well – Water System used for Photomechanical Drug Delivery
A. Mandelis, N. Baddour, Y. Cai and R. G. Walmsley, "Laser-Induced Photo-thermo-acoustic Pressure-Wave Pulses in a Polystyrene Well - Water System used for Photomechanical Drug Delivery", J.O.S.A. B 22 (5), 1024 - 1036 (May 2005). - PDF
Laser photothermoacoustic heterodyned lock-in depth profilometry in turbid tissue phantoms
Y. Fan, A. Mandelis, G. Spirou, I. A. Vitkin and W. M. Whelan, "Laser photothermoacoustic heterodyned lock-in depth profilometry in turbid tissue phantoms", Phys. Rev. E 72, 051908 (1- 11) (2005). Paper selected for inclusion in Virtual Journal of Biological Physics Research (www.vjbio.org) , 10 (10) November 15, 2005. - PDF
Bioacoustophotonic Depth-Selective Imaging of Turbid Media and Tissues: Instrumentation and Measurements
A. Mandelis "Bioacoustophotonic Depth-Selective Imaging of Turbid Media and Tissues: Instrumentation and Measurements", Physics in Canada, Special Issue on Instrumentation and Measurement Physics, Vol. 62 (2), 83 - 90 (March/April 2006). -
Development of a laser photothermoacoustic frequency-swept system for subsurface imaging: theory and experiment
Y. Fan, G. Spirou, A. Mandelis and I. A. Vitkin, "Development of a laser photothermoacoustic frequency-swept system for subsurface imaging: theory and experiment", J. Acoust. Soc. Am. 116 (6), 3523 - 3533 (December 2004). Paper selected for inclusion in Virtual Journal of Biological Physics Research (www.vjbio.org), 8 (12) Dec. 15, 2004 - PDF
Non-intrusive, non-contacting frequency-domain photothermal radiometry and luminescence depth profilometry of natural carious and artificial sub-surface lesions in human teeth
R. J. Jeon, A. Mandelis, V. Sanchez and S. H. Abrams, "Non-intrusive, non-contacting frequency-domain photothermal radiometry and luminescence depth profilometry of natural carious and artificial sub-surface lesions in human teeth", J. Biomed. Opt. 9 (4), 804 – 819 (July/August 2004). - PDF
Diagnosis of Pit & Fissure Caries using Frequency-Domain Infrared Photothermal Radiometry and Modulated Laser Luminescence
R. J. Jeon, C. Han, A. Mandelis, V. Sanchez and S. H. Abrams, "Diagnosis of Pit & Fissure Caries using Frequency-Domain Infrared Photothermal Radiometry and Modulated Laser Luminescence", Caries Res. 38, 497 – 513 (2004). - PDF
Depth profilometric case studies in caries diagnostics of human teeth using modulated laser radiometry and luminescence
R. J. Jeon, A. Mandelis and S. H. Abrams, "Depth profilometric case studies in caries diagnostics of human teeth using modulated laser radiometry and luminescence", Rev. Sci. Instrum. 74 (1), 380 - 383 (January 2003). - PDF
Quantitative Dental Measurements by use of Simultaneous Frequency-Domain Laser Infrared Radiometry and Luminescence
L. Nicolaides, C. Feng, A. Mandelis, and S. Abrams, "Quantitative Dental Measurements by use of Simultaneous Frequency-Domain Laser Infrared Radiometry and Luminescence", Appl. Opt. 41 (4), 768-777 (February 2002). - PDF
Self-Normalized Photoacoustic Thermal Diffusivity Measurements of Dental Resins
J. A. Balderas-Lopez, M. Moreno-Marquez and A. Mandelis, "Self-Normalized Photoacoustic Thermal Diffusivity Measurements of Dental Resins", Int. J. Polymeric Mat. 51, 639-646 (2002). - PDF
Novel Dental Dynamic Depth Profilometric Imaging using simultaneous Frequency-Domain Infrared Photothermal Radiometry and Laser Luminescence
L. Nicolaides, A. Mandelis and S. Abrams, "Novel Dental Dynamic Depth Profilometric Imaging using simultaneous Frequency-Domain Infrared Photothermal Radiometry and Laser Luminescence", J. Biomed. Opt. 5 (1), 31-39, January 2000. - PDF
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